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text model · Qwen2.5 · Windows

Can I run Qwen2.5 72B on Nvidia GeForce RTX 5090 (32GB)?

Compatibility verdict VRAM threshold engine
No, not enough memorywould not load

No. Qwen2.5 72B needs ~50.2 GB even at Q4_K_M, but Nvidia GeForce RTX 5090 (32GB) only has ~31 GB usable.

Needs ~50.2 GB Device usable ~31 GB

Needs ~50.2 GB even at Q4_K_M, but only ~31 GB is usable.

Q4_K_M needed
~50.2 GB
Usable on device
~31 GB
Device memory
32 GB
Model Qwen2.5
Parameters
72B
Q4_K_M size
47.42 GB
Q8_0 size
77.26 GB
Context
128k
Ollama tag
qwen2.5:72b
Full Qwen2.5 72B requirements →
Device Windows
Memory
32 GB vram
Usable for weights
~31 GB
Best runtime
vLLM (Linux) / Ollama (CUDA)
Best models for Nvidia GeForce RTX 5090 (32GB) →

What you can run instead

Run Qwen2.5 72B on other hardware

FAQ

Can Nvidia GeForce RTX 5090 (32GB) run Qwen2.5 72B?

No. Qwen2.5 72B needs ~50.2 GB even at Q4_K_M, but Nvidia GeForce RTX 5090 (32GB) only has ~31 GB usable.

How much memory does Qwen2.5 72B need?

Nvidia GeForce RTX 5090 (32GB) does not have enough memory. At Q4_K_M the weights are ~47.42 GB; with KV cache and runtime overhead, budget ~50.2 GB at a 4k context.

What is the best tool to run Qwen2.5 72B on Windows?

LM Studio for a simple setup; Ollama (CUDA) for the most speed. AMD GPUs run via Vulkan/ROCm at roughly half CUDA throughput. NVIDIA is the smooth path on Windows.

Sources

Memory figures are estimates. See methodology.